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pkc inhibitor McCaw et al s work adds important information
2018-11-07

McCaw et al.\'s work () adds important information to the growing knowledge regarding the effect of lipids on CLL cell biology, however numerous unknowns remain. For example, molecular prognostic markers in the CLL patients in these experiments are not fully detailed, LPL levels are unknown, and ser
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Glucocorticoids also exert non genomic
2018-11-07

Glucocorticoids also exert non-genomic actions that can occur rapidly within a period of several minutes. This is thought to occur through the activation of signal transduction pathways, or through the interactions of glucocorticoids with cellular membranes (Strehl and Buttgereit, 2013; Kadmiel and
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This study has several limitations First only papers publish
2018-11-07

This study has several limitations. First, only papers published in English were included. Publications in languages other than English were excluded due to insufficient information, which may lead to selection bias. Second, this study involved largely Asians and Caucasians; other ethnic subgroups (
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Although these data indicate the potential effectiveness of
2018-11-07

Although these data indicate the potential effectiveness of passive immunotherapy by NAbs, the successful development of preventive HIV-1 vaccines requires a thorough understanding of how Nabs are induced during HIV-1 infection. The unusual maturation features of NAbs make them extremely difficult t
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br Data Full length hdcA sequences of
2018-11-07

Data Full-length hdcA sequences of the histamine-producing Gram-positive bacteria strains present in Genbank database were aligned using ClustalW software [5]. Based on the alignment of these sequences Fig. 1 was made and primers used in Diaz et al. 2016 [4] were designed. For reasoning and furth
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br Acknowledgments We thank Richard A Flavell Yale Universit
2018-11-07

Acknowledgments We thank Richard A. Flavell, Yale University, and Roger J. Davis, University of Massachusetts Medical School, for their kind gift of the MKK3-deficient mice. We also thank Mary LoPresti and Jean Kanyo (Yale MS & Proteomics Resource) for their assistance with sample preparation and
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The initial Trinity de novo assembly of D japonica RNAseq
2018-11-07

The initial Trinity de novo assembly of D. japonica RNAseq data produced a dataset with 195,271 sequences and an N50 of 1,587bp. This number of contigs exceeds the number of predicted gene models in published flatworm genomes [5–9], likely due to a high number of redundant or incorrectly/partially a
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br Experimental design materials and methods We
2018-11-07

Experimental design, materials and methods We selected the four cultivars that are most widely farmed for food processing purposes. ‘Toyoshiro’ is the most popular cultivar and provides the highest yield for processing purposes in Japan [1]. ‘Kitahime’, ‘Snowden’ and ‘Poroshiri’ are predominantly
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Classification of forest stands in terms of management
2018-11-07

Classification of forest stands in terms of management and naturalness followed that of [1]. Virgin forest is almost unaffected by humans, typical by natural tree species composition, spontaneous development, multi-aged structure, long continuity. Natural forest is formed by natural processes but in
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Our perspective is not dissimilar from
2018-11-07

Our perspective is not dissimilar from Nelson\'s notion of interactive specialization of different organizing social forces at different times in development that shape social development. However, we place as much emphasis on evolutionary-based expectations of the social environment as the environm
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Coupling between vACC and PPC both at rest during the
2018-11-07

Coupling between vACC and PPC both at rest (during the rest baseline of a working memory task and during resting state fMRI) and during a working memory task have previously been shown to be associated with non-spatial working memory performance in adults (Hampson et al., 2006; Sambataro et al., 201
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A rich literature has identified a unique learning
2018-11-07

A rich literature has identified a unique learning circuit involved in the formation of attachment across a variety of species, although the neurobiology of attachment has mostly been described using rodents. Infant rodents, called pups, can neither hear nor see until the third week of life, and olf
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br Traumatic thoracolumbar spine fractures br Traumatic frac
2018-11-06

Traumatic thoracolumbar spine fractures Traumatic fractures of the thoracolumbar spine, particularly the thoracolumbar junction (T10–L2), are the most common fractures of the spinal column. Percutaneous pedicle screw instrumentation (PPSI) has been used for treating various trauma patterns. For
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In the present study there is
2018-11-06

In the present study, there is apparently no compensatory mechanism in visceral organs in order to overcome STZ induced oxidative stress. Reduced activities of SOD and CAT in liver, kidney and heart have been observed during diabetes. SOD is vital defence enzyme which catalyses the dismutation of su
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The oxidation of lipids proteins nucleic acids and carbohydr
2018-11-06

The oxidation of lipids, proteins, nucleic acids and carbohydrates generate a variety of damaging breakdown products which thus can lead to the onset of many degenerative diseases [11–15,62,63,69]. Lipid peroxidation of cell structures containing lipids can lead to the generation of different toxic
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